Table 4

 Sensitivity, specificity, and positive predictive value of risk factors associated with non-response to inhaled bronchodilator at the time of screening, and subsequent deterioration until day 5 after enrolment

SignSensitivity (%)Specificity (%)Positive predictive value (%)
Risk factors at screening
History of fever82.756.466.8
Presence of audible wheeze46.773.965.5
Temperature more than 100°F17.496.885.5
Lower chest indrawing (severe pneumonia) with wheeze54.178.973.0
Risk factors after enrolment
No family history of wheeze71.137.724.1
Temperature more than 100°F9.698.460.0
Lower chest indrawing (severe pneumonia) with wheeze40.383.637.9