Predictors identified by multivariate logistic regression* of non-response to inhaled bronchodilator at the time of screening and subsequent deterioration until day 5 after enrolment
| OR (95% CI) | p value | |
|---|---|---|
| *For modelling purpose continuous variables such as age, temperature, and duration of illness were recoded in to categorical variables. | ||
| †Against temperature ⩽100°F. | ||
| Non-response to inhaled bronchodilator at the time of screening | ||
| Screened patients (n = 1622) | ||
| History of fever | 4.06 (3.18 to 5.18) | <0.00001 |
| Presence of audible wheeze | 1.79 (1.41 to 2.26) | <0.00001 |
| Temperature more than 100°F† | 2.99 (1.89 to 4.74) | <0.00001 |
| Lower chest indrawing (severe pneumonia) with wheeze | 2.47 (1.94 to 3.14) | <0.00001 |
| Subsequent deterioration until day 5 after enrolment | ||
| Enrolled patients (n = 787) | ||
| No family history of wheeze | 1.76 (1.19 to 2.62) | 0.005 |
| Temperature more than 100°F† | 3.94 (1.66 to 9.31) | 0.002 |
| Lower chest indrawing (severe pneumonia) with wheeze | 2.96 (1.99 to 4.40) | <0.00001 |