Presentations of non-type 1 diabetes subtypes
| Presentation | Diabetes type | Investigations |
|---|---|---|
| Overweight | Type 2 | OGTT off insulin |
| May have ketoacidosis | GAD/IA-2 antibodies | |
| Insulin dose (<0.5 units/kg) | ||
| +/− Acanthosis | ||
| +/− Non-white | ||
| Diabetes | MODY | Genetic analysis |
| Dominant family history | HNF-1α | |
| Usually lean | Glucokinase | |
| Usually no ketonuria | ||
| Neonatal diabetes | ||
| UPD 6 | Genetic analysis | |
| Glucokinase | Genetic analysis | |
| Pancreatic agenesis | Ultrasound | |
| Kir 6.2 mutations | Genetic analysis79 | |
| Liver/renal impairment in diabetic child | Wolcott-Rallison | x ray hips |
| and/or | ||
| Cardiomyopathy | Alström | Ophthalmic and cardiac review |
| Diabetes and visual impairment | Alström | Ophthalmic review |
| Wolfram | ||
| Bardet-Biedl | ||
| Deafness, diabetes, and family history | Wolfram | Ophthalmic review |
| 3243 mitochondrial mutation | Genetic analysis | |
| Megaloblastic anaemia and diabetes | Roger | Hearing test |
| +/− hearing defect | Trial of thiamine | |
| Genetic analysis | ||
| Short stature and diabetes | Alström | Ophthalmic and cardiac review |
| Turner | Karyotype | |
| Bardet-Biedl | Ophthalmic review |