Baseline investigations for all infants in six studies with protocols
| A | C | D | F | G | H | A | C | D | F | G | H | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| *Performed in second year of study. | |||||||||||||
| CPK, creatinine phosphokinase. | |||||||||||||
| Note: all studies performed additional investigations in selected infants as clinically indicated. | |||||||||||||
| Basic blood tests | Metabolic work up | ||||||||||||
| FBC, U+E, glucose | + | + | + | + | + | + | Lactate, ammonia | + | − | − | − | − | − |
| Calcium, magnesium | − | + | + | + | + | + | Serum amino acids | + | − | − | − | − | + |
| Liver function tests | − | + | − | + | − | − | Urine organic acids | + | − | − | − | − | + |
| Blood gas or bicarbonate | + | + | − | + | + | + | Urine reducing substances | + | − | − | − | − | − |
| Thyroid hormones | − | − | − | − | − | + | Cardiology | ||||||
| CPK | − | + | − | − | − | − | ECG | + | + | + | + | + | + |
| Infection screen | 24 hour tape | − | − | * | − | − | − | ||||||
| Blood culture | − | − | − | − | − | − | Echocardiography | − | − | − | − | + | − |
| Urinalysis or culture | + | + | + | − | − | − | Other | ||||||
| Chest x ray | + | + | + | − | + | + | Toxicology screen | + | − | − | − | − | + |
| If secretions present: | Electroencephalogram (EEG) | − | − | − | + | + | + | ||||||
| Pertussis swab | + | − | − | − | − | − | Polysomnograph | − | + | * | − | − | + |
| Virology tests | + | − | − | − | − | − | ENT consultation | − | − | − | − | − | + |
| Bacteriological tests | − | − | − | − | − | − | Milk scan or barium swallow or pH studies | + | − | * | − | + | − |