Table 1

Comparison of etanercept and infliximab

*Costs based on a dose that does not exceed a single vial. An additional vial doubles the cost.
Licensed indicationsPolyarticular JIA failing to respond to, or intolerant of, methotrexateNot licensed
Half life70 hours200 hours
Dose0.4 mg/kg (max 25 mg) twice weekly3 mg/kg at weeks 0, 2, 6, 14, and eight weekly thereafter
Route of administrationSubcutaneous injectionIntravenous infusion
Side effectsRisk of sepsisRisk of sepsis, tachyphylaxis
Cost of vials25 mg vial: £75100 mg vial: £395 + VAT
Cost per year*£7800£4177