Table 4

 Odds ratios for the association between parental history of eczema, hayfever, and asthma and childhood atopic dermatitis, in 5658 families with complete information on parental atopy

Children with atopic dermatitis (n (%))Crude OR (95% CI)Adjusted OR (95% CI)*Adjusted OR (95% CI) controlling additionally for other parental atopic disease
*Controlling for maternal social class, paternal social class, maternal & paternal education level, parity, breast feeding; and birth weight.
CI, confidence interval; NA, not applicable; OR, odds ratio.
Parental eczema
No1046/3729 (28.1)111
Mother only453/1133 (40.0)1.71 (1.49 to 1.96)1.69 (1.47 to 1.95)1.65 (1.43 to 1.91)
Father only224/550 (40.7)1.76 (1.47 to 2.12)1.74 (1.44 to 2.09)1.60 (1.32 to 1.94)
Both parents128/246 (52.0)2.78 (2.14 to 3.60)2.72 (2.09 to 3.53)2.40 (1.83 to 3.13)
Parental asthma
No1366/4378 (31.2)11
Mother only192/544 (35.3)1.20 (0.99 to 1.45)1.18 (0.98 to 1.43)0.96 (0.79 to 1.18)
Father only245/645 (38.0)1.35 (1.14 to 1.60)1.34 (1.12 to 1.59)1.08 (0.89 to 1.30)
Both parents43/91 (52.8)2.46 (1.62 to 3.73)2.46 (1.62 to 3.75)1.63 (1.05 to 2.52)
Parental hayfever
No790/2720 (29.0)111
Mother only393/1192 (33.0)1.20 (1.04 to 1.39)1.18 (1.02 to 1.37)1.09 (0.94 to 1.28)
Father only398/1144 (34.8)1.30 (1.12 to 1.51)1.26 (1.08 to 1.46)1.17 (1.00 to 1.37)
Both parents270/602 (44.9)1.99 (1.66 to 2.38)1.92 (1.60 to 2.31)1.60 (1.32 to 1.94)
Parental atopic disease
No477/1824 (26.2)1
Mother only501/1510 (33.2)1.40 (1.21 to 1.63)1.37 (1.18 to 1.60)NA
Father only385/1183 (32.5)1.36 (1.16 to 1.60)1.32 (1.12 to 1.55)NA
Both parents488/1141 (42.8)2.11 (1.80 to 2.47)2.04 (1.74 to 2.40)NA