Table 3

Univariate analysis of clinical variables associated with hypoglycaemia in neonates

Hypoglycaemic, n (%) n=62Normoglycemic, n (%) n=204Odds ratio (95% CI)p value
n is the total number of hypoglycaemic and normoglycaemic neonates. Analysis of clinical variables done where specific data were available.
*Admitted to hospital in the preceding 14 days.
History
Last meal >12 hours11 (20.0)16 (8.3)2.8 (1.2 to 6.3)0.014
Days ill ⩾54 (6.5)21 (10.4)0.6 (0.2 to 1.7)0.354
Fever17 (27.4)89 (43.6)0.5 (0.3 to 0.9)0.022
Cough4 (6.5)53 (26.0)0.2 (0.1 to 0.5)0.019
Difficulty breathing24 (38.7)83 (40.7)0.9 (0.5 to 1.6)0.781
Vomiting1 (1.6)20 (9.8)0.2 (0.0 to 0.9)0.036
Diarrhoea2 (3.2)5 (2.5)1.3 (0.0 to 6.1)0.739
History of seizures5 (8.1)19 (9.3)0.8 (0.2 to 2.3)0.737
Uncountable seizures0 (0)2 (1.1)0.0 (0.0 to 6.4)0.435
Admhosp1*0 (0)5 (2.5)0.0 (0.0 to 2.7)0.228
Antibiotics0 (0)55 (24.9)0.0 (0.0 to 0.7)0.023
Antimalarials0 (0)12 (6.6)0.0 (0.0 to 1.0)0.051
Aspirin1 (1.8)8 (4.4)0.4 (0.0 to 2.6)0.381
Observations
Hypothermia20 (32.8)28 (13.9)3.0 (1.6 to 5.9)0.001
Hypoxia20 (33.9)38 (19.6)2.1 (1.1 to 4.0)0.022
Tachypnoea >60/min17 (27.4)64 (31.5)0.8 (0.4 to 1.5)0.539
Weight <2500 g41 (68.3)85 (41.7)3.0 (1.6 to 5.5)<0.001
Examination
Jaundice18 (29.0)67 (32.8)0.8 (0.4 to 1.5)0.513
Unconscious3 (4.8)7 (3.5)1.4 (0.4 to 5.2)0.615
Unable to breast feed39 (26.2)59 (8.9)4.1 (2.3 to 7.5)<0.001
Deep breathing8 (12.9)6 (2.9)4.8 (1.7 to 14.1)0.002
Chest in-drawing22 (35.5)73 (35.8)0.98 (0.5 to 1.8)0.965
Stiff neck3 (4.8)7 (3.4)1.4 (0.4 to 5.3)0.61
Skin infection3 (4.8)14 (6.9)0.7 (0.2 to 2.3)0.568
Basic investigation
Malaria slide positive1 (1.6%)10 (4.9%)0.3 (0 to 1.9)0.254