Presenting features of MR+ versus MR− patients
| Features | Category | MR+ patients n=10 (%) | MR− patients n=57 (%) | Difference (95% CI) | p value |
|---|---|---|---|---|---|
| *Data not available for some patients. | |||||
| SDS, standard deviation score; SEM, standard error mean. | |||||
| Age at beginning of precocious puberty (y) | ⩽4 | 4 (40) | 8 (14) | 26% (0.00 to 0.56) | 0.07 |
| >4 | 6 (60) | 49 (86) | |||
| *Bone age–chronological age (y) | ⩽2 | 1 (10) | 18 (37) | −27% (−0.45 to 0.06) | 0.145 |
| >2 | 9 (90) | 31 (63) | |||
| Tanner | |||||
| Breast stage | 1 and 2 | 2 (20) | 22 (39) | −19% (−0.39 to 0.15) | 0.311 |
| 3 and 4 | 8 (80) | 35 (61) | |||
| Pubic hair stage | 1 and 2 | 6 (60) | 35 (61) | −1% (−0.33 to 0.26) | 1.000 |
| 3 and 4 | 4 (40) | 22 (38) | |||
| Height SDS, mean (SEM) | 1.69 (0.54) | 1.17 (0.16) | 0.52 (−1.77 to 0.73) | 0.374 | |
| Body mass index SDS, mean (SEM) | 0.89 (0.24) | 0.67 (0.13) | 0.22 (−0.79 to 0.36) | 0.431 | |
| *Ultrasound pelvis | Prepubertal | 8 (80) | 46 (81) | −1% (−0.33 to 0.19) | 1.000 |
| Pubertal | 2 (20) | 11 (19) | |||
| Treatment started | 9 (90) | 45 (79) | 11% (−0.21 to 0.27) | 0.673 | |
| Treatment not started | 1 (10) | 12 (21) | |||