Table 3

Difference in percentage change in respiratory mechanics with MDI versus SVN

Time (h)Crs (SEM)pRrs (SEM)p
Statistically significant (p<0.05) differences in percentage changes in respiratory mechanics with MDI versus SVN at each sample time determined by Wilcoxon signed rank test. Values represent means (SEM).
Crs, respiratory system compliance (ml/cm H2O); Rrs, respiratory system resistance (cm H2O/ml/sec); MDI, metered dose inhaler plus spacer; SVN, small volume nebuliser.
0.5 6.6 (7.8)0.67 −6.5 (7.5)0.33
1 11.3 (10.1)0.52 −0.6 (10.4)0.95
2 −7.0 (10.5)0.58 −7.1 (17.9)0.64
4−18.6 (14.2)0.18−16.0 (19.6)0.48