Comparative evaluations of characteristics and echocardiographic parameters of left ventricular morphology in children with Down’s syndrome with and without (control group) subclinical hypothyroidism
| DS and SH n = 16 | Control group with DS n = 25 | |
|---|---|---|
| No differences between the two groups were statistically significant. | ||
| DS, Down’s syndrome; SH, subclinical hypothyroidism; BSA, body surface area; HR, heart rate; LVEDd, left ventricular end-diastolic diameter; IVSd, end-diastolic interventricular septum thickness; PWd, end-diastolic posterior wall thickness; LVMI, left ventricular mass index. | ||
| Age (months) | 65.5 (40.8) | 70.3 (27.4) |
| M/F | 7/9 | 11/14 |
| BSA (m2) | 0.62 (0.3) | 0.67 (0.2) |
| TSH values (mU/l) | Above 6.5 (mean 7.8) | Range 0.5–4.7 (mean 3.2) |
| FT3/FT4 values (mean) | 3.0/11.8 | 2.7/12.0 |
| AbTg and/or AbTPO positive/negative | 4/12 | 1/25 |
| HR (beats/min) | 87.3 (18.9) | 84.2 (16.9) |
| LVEDd (mm) | 31.4 (4) | 32.6 (3) |
| IVSd (mm) | 5.4 (0.7) | 6 (0.6) |
| PWd (mm) | 4.9 (1.1) | 5.2 (0.7) |
| LVMI (g/m2) | 58.3 (10.4) | 54.3 (7.7) |