Table 3

Change in the prevalence of congenital anomalies, Glasgow, 1980–97

Congenital anomaly category	Slope of regression line*	% change†	p value
*Average change in rate per 10000 per year.
†Percentage change in the prevalence from 1980 to 1997.
Congenital heart disease	−2.89	−69	<0.001
Neural tube defects	−1.55	−63	<0.001
Nervous system anomalies	−1.59	−61	<0.001
Anomalies of limb	−1.69	−54	<0.001
Other anomalies	−0.926	−64	0.002
Down's syndrome	0.606	100	0.003
Integument anomalies	−0.329	−67	0.007
Genitourinary tract and kidney	−0.67	−31	0.013
Ear anomalies	−0.194	−88	0.015
Chromosomal anomalies (total)	0.598	50	0.015
Metabolic defects	−0.236	−20	0.164
Respiratory system anomalies	0.143	150	0.204
Eye anomalies	−0.064	−25	0.436
Cleft lip with/without palate	0.041	8	0.744
Musculoskeletal and connective tissue anomalies	0.052	4	0.875
Digestive system anomalies	−0.046	−2	0.917

Total	−7.78	−34	<0.001