Positive autoantibodies and clinical symptoms in children with 22q11.2 deletion
| Patient | Age (y) | Sex | Autoantibodies | Clinical symptoms |
|---|---|---|---|---|
| RhF, rheumatoid factor; GPC, gastric parietal cell; ANA, antinuclear antibody; AECA, antiendothelial antibody; SM, smooth muscle. | ||||
| 2 | 7 | F | Persistent +ve RhF | Raynaud's phenomenon |
| 3 | 12 | F | Persistent +ve RhF | Evans syndrome |
| 4 | 9 | F | +ve GPC | Pauciarticular arthritis |
| 5 | 12 | F | Transient +ve ANA | Nil |
| 6 | 22 | F | +ve thyroid microsomal, +ve ANA, +ve cardiolipin, +ve AECA antibodies | Raynaud's phenomenon, vasculitis |
| 7 | 4 | M | +ve antiplatelet antibody | Thrombocytopenia |
| 8 | 12 | F | Nil | Urticaria, Raynaud's phenomena |
| 9 | 8 | M | Transient +ve GPC | Nil |
| 13 | 9 | M | Transient +ve SM antibody | Nil |
| 27 | 4 | M | Persistent +ve RhF | Nil |