Table 1

Classification of renal stones in childhood

Struvite stones (radio-opaque)
Associated with urinary tract infections (often proteus)
Calcium stones (radio-opaque)
See fig 1
Oxalate stones (radio-opaque)
Primary hyperoxaluria type I
Primary hyperoxaluria type II
Enteric hyperoxaluria
Idiopathic
Uric acid stones (radiolucent)
Familial
Over production
• Hypoxanthine guanine phosphoribosyl transferase (HGPRT) deficiency
• Glucose-6-phosphatase (G-6-P) deficiency
• Phosphoribosyl pyrophosphate synthetase (PRPs) superactivity
• Adenine phosphoribosyl transferase (APRT) deficiency
Hyperuricosuria
• Related to high purine diet
• Tumourlysis
• Chronic volume contraction associated with bicarbonate losses, e.g. chronic diarrhoea, short gut syndrome
Stones associated with hypocitraturia
Cystine stones (usually radio-opaque)
Cystinuria
Other metabolic disorders (radiolucent)
Xanthinuria
Orotic aciduria