Classification of renal stones in childhood
Struvite stones (radio-opaque) |
Associated with urinary tract infections (often proteus) |
Calcium stones (radio-opaque) |
See fig 1 |
Oxalate stones (radio-opaque) |
Primary hyperoxaluria type I |
Primary hyperoxaluria type II |
Enteric hyperoxaluria |
Idiopathic |
Uric acid stones (radiolucent) |
Familial |
Over production |
• Hypoxanthine guanine phosphoribosyl transferase (HGPRT) deficiency |
• Glucose-6-phosphatase (G-6-P) deficiency |
• Phosphoribosyl pyrophosphate synthetase (PRPs) superactivity |
• Adenine phosphoribosyl transferase (APRT) deficiency |
Hyperuricosuria |
• Related to high purine diet |
• Tumourlysis |
• Chronic volume contraction associated with bicarbonate losses, e.g. chronic diarrhoea, short gut syndrome |
Stones associated with hypocitraturia |
Cystine stones (usually radio-opaque) |
Cystinuria |
Other metabolic disorders (radiolucent) |
Xanthinuria |
Orotic aciduria |