Ability of the clinical findings to predict meningococcal infection
Sensitivity | Specificity | PPV | NPV | |
---|---|---|---|---|
Variable | % | % | % | % |
Illness | 79 (63 to 95) | 81 (76 to 87) | 35 (22 to 47) | 97 (91 to 100) |
Purpura | 83 (68 to 98) | 88 (84 to 93) | 47 (32 to 61) | 98 (92 to 100) |
Rash beyond SVC | 100 (94 to 100) | 38 (31 to 45) | 17 (11 to 23) | 100 (91 to 100) |
Fever >38.5°C | 58 (39 to 78) | 81 (75 to 86) | 27 (15 to 40) | 94 (88 to 100) |
Fever >37.5°C | 79 (63 to 95) | 55 (48 to 62) | 18 (11 to 25) | 95 (88 to 100) |
Hypotension | 28 (7 to 48) | 97 (93 to 100) | 71 (38 to 100) | 84 (75 to 92) |
Capillary refill >2 seconds | 83 (68 to 98) | 85 (81 to 90) | 42 (28 to 56) | 98 (92 to 100) |
95% CI in parentheses.
PPV, positive predictive value; NPV, negative predictive value; SVC, superior vena cava.