Modes of action in groups of OTC cough medicines
| Antitussives | Centrally acting opioid derivates or peripherally acting agents16 |
| Mucolytics | Aiming to decrease the viscosity of bronchial secretions, making them easier to clear through coughing17 |
| Antihistamineādecongestant combinations | Combine histamine H1 receptor antagonists and Ī± adrenoceptor agonists which cause vasoconstriction of mucosal blood vessels18 |
| Other drug combinations | Fixed drug combinations using different ingredients |
| Antihistamines | Histamine H1 receptor antagonists |