Predictive value of clinical signs for hypoxaemia (Spo2 <86%) in the sick neonates
| Sign | Number with sign/number recorded | Odds ratio (95% CI) | p value | Sensitivity | Specificity | PPV | NPV |
|---|---|---|---|---|---|---|---|
| Not feeding | 75/130 | 1.9 (0.95–4.0) | 0.07 | 66.7 | 49.3 | 50.7 | 65.4 |
| Cyanosis | 49/132 | 21.5 (8.4–54.6) | <0.0001 | 71.9 | 89.3 | 83.7 | 80.7 |
| Reduced activity | 55/132 | 4.4 (2.1–9.2) | <0.0001 | 61.4 | 73.3 | 63.6 | 71.4 |
| Respiratory rate >60 | 41/132 | 1.2 (0.57–2.53) | 0.62 | 33.3 | 70.7 | 46.3 | 58.2 |
| RR <30 | 7/132 | 8.7 (1.0–74.5) | 0.048 | 10.5 | 98.7 | 85.7 | 59.2 |
| Failed to resist examination | 35/126 | 3.7 (1.6–8.4) | 0.002 | 42.6 | 83.3 | 65.7 | 65.9 |
| Head nodding | 2/132 | 3.5 | 100 | 100 | 57.6 | ||
| Grunting | 19/132 | 3.4 (1.2–9.6) | 0.021 | 22.8 | 92.0 | 68.4 | 61.1 |