Children who did not complete the trial
| Group | Age (y) | Sex | When withdrew (wk) | Pain score on withdrawal | Reason |
| GTN | 2.4 | F | 7 | 0 | Lost contact |
| GTN | 2.7 | F | 11 | 8 | Persistent high pain scores; no fissure when examined under anaesthetic |
| GTN | 1.3 | F | 5 | 8 | Persistent high pain scores; coryzal symptoms thought by parents to be due to GTN |
| GTN | 0.7 | M | 1 | 10 | No reason given |
| GTN | 1.2 | F | 4 | 8 | Perineal rash; examination under anaesthetic at week 4: fissure healed, pain free at 8 weeks and off laxatives |
| GTN | 1.2 | M | 1 | 8 | Gastrointestinal upset (colicky pains and vomiting) |
| GTN | 3.6 | F | 14 | 2 | Parental dissatisfaction with improvement; underwent fissurectomy |
| Placebo | 1.8 | F | 8 | 9 | Persistent high pain scores; underwent fissurectomy |
| Placebo | 2.6 | M | 8 | 7 | Persistent high pain scores; underwent fissurectomy |