Table 1

The amount (minutes/day; median with interquartile range) of fussing and crying, and total distress reported by parents during the seventh and twelfth weeks of life

		Controls	Children with atopic disease	Mann–Whitney U test p value
During the seventh week
Fussing^1-150		41 (19–75)	72 (15–131)	0.02
Cry	Colic type^1-151	4 (0–17)	6 (0–19)	0.35
	Other^1-151	24 (15–49)	30 (15–45)	0.71
Total distress^1-152		89 (47–124)	115 (64–197)	0.06

During the twelfth week
Fussing^1-150		21 (4–45)	29 (11–66)	0.13
Cry	Colic type^1-151	0 (0–5)	5 (0–11)	0.04
	Other^1-151	13 (2–22)	14 (4–41)	0.22
Total distress^1-152		43 (21–68)	71 (24–109)	0.12

↵1-150 Fussing was defined as a state of irritability, “not quite crying but not awake and content”.5
↵1-151 Other cry was defined as crying responsive to intervention (feeding, change of diaper, carrying, sucking a pacifier); colic type cry was defined as a cry not responsive to such an intervention.
↵1-152 The sum of colic type cry, other cry, and fussing reported by parents.