Histological findings in patients
| Case | 1 | 2 | 3 | 4 | 5 | 6 | 7 |
| Duration before biopsies | 4 years and 6 months | 8 months | 22 months | 3 months | 3 years and 9 months | 2 years and 2 months | 5 years and 4 months |
| Cellularity | Marked, transmural | Marked, transmural | Marked | Marked with plasma cells | Marked with plasma cells | Marked | Marked |
| Surface | Flat or mildly irregular, mild invasion | Flat, irregular with degeneration and erosion | Flat, midly irregular | Irregular, invasion and flattening | Irregular with flattening, erosion and invasion | Irregular, inflamed | Flat, moderate inflammation |
| Nuclear debris | Yes | No | Yes | Few | Yes | Yes | Few |
| Crypts | Mild to moderate distortion. Very mild cryptitis | Moderate to severe distortion. Mild to severe cryptitis | Mainly normal architecture, mild reduction in number. Mild cryptitis | Mild to moderate distortion, with reduced number. Mild to moderate cryptitis | Moderate modified architecture, mild reduced number. Moderate cryptitis | Normal architecture. No cryptits | Normal architecture. No cryptitis |
| Crypt abscess | None | Crypt abscesses in a/d | None | Mild in sigmoid | None | None | None |
| Polymorphs | Eosinophils +++ | Eosinophils | Eosinophils +++ | Eosinophils + | Eosinophils + | Eosinophils ++ | Eosinophils + |
| Histocytes | Mild increase in histocytes, macrophages with pigments | Few macrophages with pigments | Macrophages with eosinophilic materiel | Few macrophages with pigments | Foamy, starting to form a granuloma with eosinophilic material | Macrophages with pigments | Few macrophages with pigments |
| Granuloma | None | Very big, with giants cells in a/t/d/s/r | None | None | In d/s | None | None |
| Vessels | Plump vessels, thick walls. Trafficking eosinos | Plump endothelium, eosinos trafficking | Abnormal in caecum | Plump, eosinos trafficking | Plump endothelium | Plump endothelium | Plump endothelium |
A, ascending; t, transverse; d, descending; s, sigmoid; r, rectum; eosinos, eosinophils.