Table 5

Outcome of five trials of corticosteroid therapy in children with relapsing steroid responsive nephrotic syndrome

Author, year Relapse on therapy, RR (95% CI) Relapse by 9 months, RR (95% CI) Relapse by 12 months, RR (95% CI) Mean relapse rate during study, WMD (95% CI)
ISKDC, 197925 0.20 (0.05, 0.82)1.00 (0.89, 1.12)0.54  (−0.50, 1.58)
APN, 198116 0.60 (0.36, 1.02)1.20 (0.93, 1.55)−0.20 (−0.65, 0.25)
Imbascialiet al, 198526 1.06 (0.75, 1.52)
Ekka et al, 199727 1.07 (0.77, 1.50)
Broyer et al, 199728 0.44 (0.25, 0.78)−1.90 (−2.77, −1.03)
  • RR, relative risk; WMD, weighted mean difference.

  • ISKDC, International Study of Kidney Disease in Children.

  • APN, Arbeitsgemeinschaft für Pädiatrische Nephrologie.