Comparing measured drug adherence between morning and evening doses, when treating mild childhood asthma with inhaled budesonide or placebo for 27 months
Months | Morning | n | Evening | n | p value |
3 | 76.7 (72.2–81.2) | 122 | 77.6 (73.8–81.5) | 122 | NS |
9 | 51.7 (46.4–57.0) | 115 | 58.8 (53.6–64.0) | 114 | <0.001 |
15 | 47.7 (41.9–53.5) | 103 | 55.3 (49.4–61.1) | 101 | <0.001 |
21 | 43.6 (37.2–50.0) | 93 | 50.3 (43.4–57.2) | 93 | <0.001 |
27 | 40.6 (32.5–48.7) | 62 | 46.9 (38.8–55.0) | 61 | 0.02 |
Mean values are given as percentages (95% CI). NS, non-significant.