Neurotransmitter | GnRH regulation | Appetite regulation |
γ-Aminobutyric acid | Y (−) | Y (+) |
Glutamate | Y (+) | Y (+) |
Neuropeptide Y1-150 | Y (− & +) | Y (+) |
Galanin | Y (+) | |
Melanin concentrating hormone | Y (+) | |
Orexins | Y (+) | |
Leptin | Y (+) | Y (−) |
CART1-150 | Y (+) | Y (−) |
Pro-opiomelanocortin1-150 | Y (+) | Y (−) |
Melanocyte stimulating hormone | Y (−) | |
Corticotrophin releasing hormone | Y (−) | |
Agouti related protein | Y (−) | |
Urocortin | Y (−) | |
Glucagon-like peptide-1 | Y (−) |
↵1-150 Factors that may act to mediate the relation between leptin and GnRH secretion.
The sign in parentheses denotes activation/increase or inhibition/decrease.
CART, cocaine and amphetamine regulated transcript.