Association between dietary control between 0 and 8 years and verbal, performance, and full scale IQ standard deviation scores (IQ-SDS) at 8, 14, and 18 years
| Category | p Value4-150 | ||||
|---|---|---|---|---|---|
| 1 (best) | 2 | 3 | 4 (worst) | ||
| 8 years IQ-SDS | (n = 15) | (n = 51) | (n = 25) | (n = 13) | |
| Verbal | −0.22 (−0.69 to 0.24) | −0.26 (−0.58 to 0.06) | −1.05 (−1.58 to −0.52) | −1.11 (−1.69 to −0.53) | 0.007 |
| Performance | −0.61 (−0.95 to −0.28) | −0.71 (−1.02 to −0.39) | −1.43 (−1.88 to −0.98) | −1.66 (−2.04 to −1.29) | 0.001 |
| Full Scale | −0.39 (−0.77 to −0.01) | −0.47 (−0.80 to −0.15) | −1.32 (−1.82 to −0.82) | −1.47 (−1.92 to −1.01) | 0.001 |
| 14 years IQ-SDS | (n = 6) | (n = 31) | (n = 20) | (n = 12) | |
| Verbal | −1.03 (−2.36 to 0.31) | −0.46 (−0.91 to −0.01) | −1.33 (−1.82 to −0.84) | −1.70 (−2.15 to −1.25) | 0.006 |
| Performance | −0.61 (−2.03 to 0.81) | −0.67 (−1.13 to −0.21) | −1.36 (−1.79 to −0.92) | −1.72 (−2.32 to −1.11) | 0.02 |
| Full Scale | −0.85 (−2.29 to 0.59) | −0.52 (−0.99 to −0.05) | −1.41 (−1.85 to −0.97) | −1.82 (−2.34 to −1.30) | 0.004 |
| 18 years IQ-SDS | (n = 2) | (n = 21) | (n = 14) | (n = 10) | |
| Verbal | −1.57 (−3.53 to 0.40) | −0.91 (−1.32 to −0.51) | −1.06 (−1.60 to −0.52) | −1.49 (−2.08 to −0.90) | 0.34 |
| Performance | −1.57 (−9.89 to 6.76) | −0.91 (−1.30 to −0.52) | −0.96 (−1.61 to −0.31) | −1.83 (−2.28 to −1.37) | 0.06 |
| Full Scale | −1.64 (−6.27 to 3.00) | −0.94 (−1.33 to −0.55) | −1.09 (−1.65 to −0.53) | −1.72 (−2.23 to −1.20) | 0.12 |
Results are expressed as mean (95% confidence interval).
Categories: 1, 75–100% phenylalanine concentrations between 125 and 500 μmol/litre; 2, 50–74% phenylalanine concentrations between 125 and 500 μmol/litre; 3, 25–49% phenylalanine concentrations between 125 and 500 μmol/litre; 4, 0–24% phenylalanine concentrations between 125 and 500 μmol/litre.
↵4-150 One way analysis of variance.