Serum analyte concentrations in children with asthma before and after oral prednisolone treatment, and the normal controls
| Analyte | Serum concentration | Controls | p Value2-150 | p Value2-151 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Before | After | ||||||||
| IL-5 | 5.59 (0.71) | 2.19 (0.18) | ND | 0.0001 | 0.03 | ||||
| IL-4 | 0.56 (0.25) | 2.20 (1.13) | ND | NS | NS | ||||
| sCD25 | 2236 (192) | 1172 (175) | 506 (34) | 0.002 | 0.03 | ||||
| ECP | 54.3 (4.7) | 33.1 (3.7) | 15.5 (1.9) | 0.0001 | 0.03 | ||||
Values are mean (SEM) expressed as pg/ml. Measurements below the detection limit of the assays (ND) were regarded as zero.
↵2-150 Student's paired t test comparing children with asthma before and after treatment.
↵2-151 Wilcoxon signed ranks test comparing chidren with asthma after treatment and controls.
IL, interleukin; sCD25, soluble CD25; ECP, eosinophil cationic protein.