Prevalence of caffeine consumption in four strata during and after pregnancy in SIDS cases and controls with crude and adjusted odds ratios (ORs) in Scandinavia 1992–95, the Nordic epidemiological SIDS study
Caffeine consumption | Cases | Controls | Crude | Adjusted for smoking in 1st trimester | Adjusted for maternal age, education, parity, and smoking in 1st trimester | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
OR | 95% CI | p Value | OR | 95% CI | p Value | OR | 95% CI | p Value | |||||||
During pregnancy | |||||||||||||||
Nil | 34 | 160 | 1.0 | Ref | Ref | 1.0 | Ref | Ref | 1.0 | Ref | Ref | ||||
1–400 mg/24 h | 102 | 465 | 0.9 | 0.6 to 1.5 | 0.74 | 0.9 | 0.6 to 1.5 | 0.70 | 1.1 | 0.6 to 1.9 | 0.79 | ||||
401–800 mg/24 h | 57 | 119 | 2.0 | 1.2 to 3.4 | 0.009 | 1.2 | 0.7 to 2.2 | 0.46 | 1.5 | 0.8 to 3.0 | 0.20 | ||||
> 800 mg/24 h | 24 | 24 | 3.9 | 1.9 to 8.1 | < 0.001 | 1.7 | 0.8 to 3.8 | 0.19 | 2.5 | 1.0 to 6.7 | 0.06 | ||||
After pregnancy | |||||||||||||||
Nil | 28 | 109 | 1.0 | Ref | Ref | 1.0 | Ref | Ref | 1.0 | Ref | Ref | ||||
1–400 mg/24 h | 98 | 478 | 0.7 | 0.4 to 1.2 | 0.16 | 0.7 | 0.4 to 1.2 | 0.12 | 0.9 | 0.5 to 1.5 | 0.60 | ||||
401–800 mg/24 h | 59 | 158 | 1.2 | 0.7 to 2.1 | 0.45 | 0.9 | 0.5 to 1.6 | 0.20 | 1.0 | 0.5 to 2.0 | 0.91 | ||||
> 800 mg/24 h | 30 | 30 | 3.1 | 1.5 to 6.3 | 0.002 | 1.4 | 0.6 to 3.1 | 0.62 | 2.0 | 0.8 to 5.2 | 0.14 |
CI, confidence interval.