Table 2

Standing height and endocrine findings in osteogenesis imperfecta (OI)

Standing height(Standing height SDS) − (target height SDS)(Standing-height SDS) − (mean height of unaffected family members SDS)IGF-IIGFBP-3
Mean SDSStudent’s t testDifferenceStudent’s t testDifferenceStudent’s t testMean SDSStudent’s t testMean SDSStudent’s t test
Children
Sillence type
 I−1.01:3/4
p < 0.01		−0.11:3/4
p < 0.01		−1.11:3/4
p < 0.01		−0.51:3/4
p < 0.05		−0.4NS
 III−6.2−6.1−6.6−1.0−1.0
 IV−3.2−0.9−2.8−1.2−0.6
Collagen type
 Quantitative−1.3p < 0.01−0.34p < 0.01−0.9p < 0.01−0.4NS−0.2p < 0.05
 Qualitative−5.4−4.9−5.5−1.0−1.0
Adults
Sillence type
 I−2.131:3/4
p < 0.01		−1.11:3/4
p < 0.01		−1.51:3/4
p < 0.05		NANANANA
 III−10.6−10.8−11.2NANA
 IV−3.4−1.5−2.0NANA
Collagen defect
 Quantitative−1.9p < 0.01−0.7p < 0.01−1.2p < 0.01NANANANA
 Qualitative-6.4−5.2−5.9NANA

  • The Student’s t test was performed between OI type I and type III/IV (1:3/4), as well as between quantitative and qualitative collagen defects.

  • NS, not significant; NA, not available.