Table 6

Survival of treated children by treatment centre and entry into national trials

		5 year % survival (SE)		All children			First 3 months			3 months to 2 years			After 2 years
		5 year % survival (SE)		O	E	p Value		O	E	p Value		O	E	p Value		O	E	p Value
1980–84
< 1/year	59 (3.8)	78	72.3	0.18		7	8.4	0.77		37	32.4	0.23		34	31.5	0.42
1–3/year	66 (3.1)	97	87.3			15	10.8			37	34.6			45	41.9
6–45/year	69 (1.4)	453	470.4			52	54.8			180	187.0			223	228.6
1985–89
< 1/year	76 (4.8)	21	25.3	0.15		2	2.7	0.90		6	8.2	0.29		13	14.4	0.30
1–3/year	79 (2.9)	53	59.3			10	9.2			14	15.7			29	34.4
6–45/year	73 (1.2)	433	422.4			46	46.1			152	148.1			235	228.2
1990–94
< 1/year	78 (6.0)	12	9.7	0.48		4	1.8	0.11		0	1.5	0.12		8	6.4	0.27
1–3/year	80 (2.8)	43	42.6			6	6.2			9	11.5			28	25.0
6–45 year	82 (1.0)	295	297.7			40	42.0			104	100.0			151	155.7
1980–84
UKCCSG	69 (1.3)	473	482.5	0.31		56	56.6	0.84		182	190.5	0.16		235	235.4	0.94
Other	64 (2.5)	157	147.5			18	17.4			72	63.5			67	66.6
1985–89
UKCCSG	73 (1.2)	443	431.8	0.11		49	47.4	0.54		155	150.2	0.22		239	234.2	0.38
Other	78 (2.7)	64	75.2			9	10.6			17	21.8			38	42.8
1990–94
UKCCSG	82 (1.0)	308	312.9	0.31		41	44.3	0.064		106	104.3	0.53		161	164.3	0.37
Other	79 (3.0)	42	37.1			9	5.7			7	8.7			26	22.7
1980–84
Trial	70 (1.5)	347	352.6	0.62		52	39.8	0.0016		128	130.4	0.73		167	182.4	0.053
Non-trial	64 (1.9)	283	277.4			22	34.2			126	123.6			135	119.6
1985–89
Trial	77 (1.2)	394	409.9	0.023		38	41.9	0.14		116	127.3	0.011		240	240.7	0.86
Non-trial	60 (3.0)	113	97.1			20	16.1			56	44.7			37	36.3
1990–94
Trial	84 (1.0)	242	273.9	< 0.0001		21	35.1	< 0.0001		81	90.2	0.014		140	148.5	0.079
Non-trial	68 (2.6)	108	76.1			29	14.9			32	22.8			47	38.5

The expected numbers of deaths and log rank tests based on stratified analyses allowing for age, sex, white blood cell count, immunophenotype, and Down’s syndrome status.
O, observed deaths; E, expected deaths; P, two sided p value from log rank test; UKCCSG, UK Children’s Cancer Study Group.