Outcome for 45 children with Down’s syndrome aged 1 year or older receiving chemotherapy
| Type of treatment | n | Number remitting (%) | Overall survival at 5 years, % (SE) | Relapse risk at 5 years, % (SE) |
|---|---|---|---|---|
| Any | 45 | 38 (84) | 55 (7.5%) | 26 (8.0%) |
| On protocol (groups A and B) | 32 | 26 (81)¶ 3-150 | 59 (8.7%)3-151 ** | 16 (8.3%)*** |
| Individual (group C) | 13 | 12 (92)§ | 43 (14.7%)‡ | 46 (15.0%) |
↵3-150 p = 0.7; **p = 0.9; ***p = 0.08; p values are for Fisher’s exact test (remission rate and deaths in remission) and log rank test (overall survival and relapse risk).
↵3-151 One alive in relapse; ‡one alive in second complete remission;§single remission failure as a result of resistant disease; ¶all remission failures as a result of death during first course of treatment.