Clinical features in Noonan’s syndrome
| Patient | Sex | Age1-150(years) | Gut symptoms | Foregut pathology | Cardiology diagnosis |
|---|---|---|---|---|---|
| 1 | F | 5 | None | – | HC |
| 2 | F | 3 | None | – | Normal |
| 3 | F | 0.03 | PF + C | – | PS |
| 4 | F | 0.1 | V | – | PS |
| 5 | F | 0.08 | PF + V + Ab pain, D + C | GOR + malrotation | PS |
| 6 | F | 1 | PF | – | PS |
| 7 | F | 0.08 | PF | – | PS |
| 8 | F | 0.08 | PF +V + Ab pain, D + C | GOR | Normal |
| 9 | M | 8 | None | – | HC |
| 10 | M | 4 | None | – | Normal |
| 11 | M | 4 | None | – | Normal |
| 12 | M | 8 | None | – | PS |
| 13 | M | 1 | PF +V + Ab pain, D + C | GOR | PS |
| 14 | M | 3 | None | – | PS |
| 15 | M | 11 | None | – | PS |
| 16 | M | 0.25 | PF + V + C | – | PS |
| 17 | M | 0.16 | PF +V + Ab pain, D+ C | GOR + malrotation | HC |
| 18 | M | 0.08 | PF | – | HC |
| 19 | M | 0.08 | PF +V + Ab pain, D + C | GOR | PS |
| 20 | M | 0.08 | PF +V + Ab pain, D + C | GOR | PS |
| 21 | M | 0.08 | PF | – | PS |
| 22 | M | 0.33 | PF | – | Normal |
| 23 | M | 1 | V | – | HC |
| 24 | M | 3 | None | – | HC |
| 25 | F | 1.5 | PF +V + Ab pain, D + C | GOR | HC |
↵1-150 Age at presentation.
PF, poor feeding; V, vomiting; D, abdominal distension; C, constipation; GOR, gastro-oesophageal reflux; Ab pain, abdominal pain; PS, pulmonary stenosis; HC, hypertrophic cardiomyopathy.