One, five, and 10 year survival (%) after ALL in childhood (with 95% confidence intervals), by deprivation category and calendar period of diagnosis with mean percentage change in survival between successive five- year calendar periods: England and Wales, patients diagnosed 1971–90
| Deprivation category | 1 year survival | Mean % change2-150 | 5 year survival | Mean % change2-151 | 10 year survival | Mean % change2-152 | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1971–75 | 1976–80 | 1981–85 | 1986–90 | 1971–75 | 1976–80 | 1981–85 | 1986–90 | 1971–75 | 1976–80 | 1981–85 | ||||
| 1 (affluent) | 79 (74, 84) | 82 (78, 86) | 89 (85, 92) | 94 (91, 96) | 5.2 (2.9, 7.5) | 40 (34, 46) | 52 (46, 57) | 72 (67, 76) | 79 (74, 83) | 13.7 (6.5, 20.9) | 35 (29, 40) | 48 (42, 43) | 64 (58, 69) | 14.5 (3.5, 25.5) |
| 2 | 77 (71, 82) | 85 (82, 90) | 88 (83, 91) | 92 (89, 95) | 4.7 (0.3, 9.1) | 43 (37, 50) | 57 (51, 62) | 70 (65, 76) | 76 (71, 81) | 11.2 (5.5, 16.9) | 33 (27, 39) | 51 (45, 56) | 66 (60, 71) | 16.5 (5.5, 27.5) |
| 3 | 72 (66, 78) | 81 (75, 85) | 89 (84, 92) | 94 (90, 97) | 7.4 (4.6, 10.2) | 44 (37, 51) | 51 (45, 57) | 72 (66, 77) | 78 (72, 83) | 12.3 (3.45, 21.1) | 34 (27, 40) | 43 (37, 49) | 64 (58, 70) | 15.0 (−29.0, 59.0) |
| 4 | 82 (76, 86) | 82 (77, 87) | 84 (79, 88) | 94 (90, 96) | 3.8 (−3.2, 10.8) | 45 (39, 51) | 58 (52, 64) | 68 (62, 74) | 74 (68, 79) | 9.7 (4.9, 14.5) | 37 (30, 43) | 51 (45, 57) | 65 (58, 71) | 14.02-153 |
| 5 (deprived) | 78 (72, 83) | 79 (74, 84) | 86 (81, 90) | 89 (85, 93) | 4.0 (0.7, 7.3) | 44 (37, 51) | 48 (42, 54) | 67 (61, 73) | 76 (70, 80) | 11.5 (3.2, 19.8) | 36 (30, 43) | 42 (35, 48) | 62 (56, 68) | 13.0 (−38.3, 64.3) |
| Log rank test2-154 | 0.18 | 0.32 | 0.44 | 0.16 | 0.83 | 0.10 | 0.66 | 0.77 | 0.78 | 0.96 | 0.08 | |||
↵2-150 Mean percentage change in survival to one year between successive five-year calendar periods; percentage change is significant if confidence intervals do not include zero.
↵2-151 Mean percentage change in survival to five years between successive five-year calendar periods; percentage change is significant if confidence intervals do not include zero.
↵2-152 Mean percentage change in survival to 10 years between successive five-year calendar periods; percentage change is significant if confidence intervals do not include zero.
↵2-153 Although an increase of 14% is significant, confidence limits cannot be calculated in this instance because the regression line described by these three survival estimates has a standard error of zero.
↵2-154 p values for log rank test comparing survival one, five, and 10 years after diagnosis for children in each deprivation category, after excluding cases for whom a deprivation category could not be assigned.