Clinical charactistics of varicella zoster virus associated complications
| Characteristic | Complication | p value | |||
|---|---|---|---|---|---|
| CNS (n = 26) | Bacterial (n = 32) | Other (n = 55) | Total (n = 113) | ||
| Median age in years (interquartile range) | 6.6 (4.5, 7.7) | 2.8 (1.2, 6.3)3-150 | 5.6 (2.2, 7.6) | 5.6 (2.0, 7.6) | 0.493-150 |
| Number (%) of female patients | 10 (38) | 14 (44) | 30 (55) | 54 (48) | |
| Number (%) with pre-existing illness | 1 (4)3-151 | 5 (16) | 19 (35) | 25 (22) | 0.013-151 |
| Interval from onset of varicella to onset of complication (days) (SD) | 5.2 (2.7)3-152 | 2.4 (1.7) | 2.3 (2.5) | 3.0 (2.6) | < 0.00013-152 |
| Interval from onset of varicella to admission (days) (SD) | 7.4 (3.1)3-152 | 3.9 (2.3) | 3.2 (2.9) | 4.3 (3.2) | < 0.00013-152 |
| Maximum temperature (°C) (SD) | 37.4 (1.0) | 39.1 (1.1)3-152 | 38.7 (1.2) | 38.5 (1.3) | 0.0013-152 |
| Number (%) with maximum temperature > 38.0°C | 4 (15)3-151 | 27 (84)3-151 | 38 (69) | 69 (61) | < 0.013-151 |
| Mean (SD) peripheral WBC count (× 109/l) | 8.5 (4.5) | 11.1 (5.0)3-152 | 8.5 (4.8) | 9.2 (4.9) | 0.023-152 |
| Number (%) with immature WBC count > 15% | 03-151 | 15 (47) | 11 (20) | 26 (23) | 0.0023-151 |
| Number (%) with intensive care unit admission | 2 (8) | 1 (3) | 3 (5) | 6 (5) | |
| Mean (SD) duration of hospitalisation (days) | 9.0 (4.9) | 7.9 (6.0) | 5.7 (3.9) | 7.1 (5.0) | |