Baseline data and the effect of phase I medications on outcome variables at day 5–7
| Outcome variable | Placebo | Salbutamol | p value2-150 |
|---|---|---|---|
| Cough frequency (number in 24 hours) | |||
| Baseline, geometric mean (SD) | 85 (3.5) | 53 (2.6) | |
| % change, mean (95%CI) | −34 (−60, 8) | −45 (−74, 163) | 0.24 |
| Symptom score (parent completed) | |||
| Baseline, median (IQR) | 4.5 (2.8) | 3.1 (3) | |
| Change, mean (95%CI) | −0.5 (−1.6, 0.6) | −0.9 (−2, 0.3) | 0.12 |
| Symptom score (child completed) | |||
| Baseline, median (IQR) | 3.9 (3.8) | 3 (2.5) | |
| Change, mean (95%CI) | −1.2 (−2.3, 0.02) | −0.9 (−2, 0.1) | 0.31 |
| Log10 Cth (μmol) | |||
| Baseline, median (IQR) | 0.84 (1.05) | 0.99 (0.6) | |
| Change, mean (95%CI) | 0.07 (−0.22, 0.36) | 0.14 (−0.11, 0.39) | 0.45 |
| Log10 C5 (μmol) | |||
| Baseline, median (IQR) | 1.29 (1.02) | 1.44 (0.6) | |
| Change, mean (95%CI) | 0.16 (−0.17, 0.49) | 0.2 (−0.1, 0.49) | 0.34 |
↵2-150 Comparison of change between the groups (linear regression adjusted for baseline).
IQR, interquartile range.