Diagnosis | No of cases | Biochemical response (yes/no) | Clinical response (yes/no) | Reference |
---|---|---|---|---|
PDC (unspecified) | 10 | 7/3 | 2/2 | 23, 24, 27,3-150 |
PDC E1 | 4 | 2/2 | 0/4 | 25-28,3-150 |
PDC E2 | 1 | 1/0 | 0/1 | 29 |
PDC E3 | 2 | 1/1 | 1/1 | 21,3-150 |
Complex I | 1 | 1/0 | 1/0 | 30 |
Complex IV | 6 | 3/3 | 1/4 | 12, 27, 31, 32, 46 |
Complex I, IV | 1 | 1/0 | 0/1 | 32 |
PC, PEPCK | 2 | 2/0 | 0/2 | 33 |
Leigh’s syndrome | 2 | 2/0 | 0/1 | 34,3-150 |
MELAS3-151 | 5 | 4/1 | 3/1 | 19, 20, 35, 36,3-150 |
MERRF | 4 | 4/0 | 1/2 | 37, 38, 46 |
Pearson’s syndrome | 1 | 1/0 | 1/0 | 3-150 |
Unknown | 12 | 11/1 | 5/5 | 12, 37, 39-44, 47,3-150 |