Table 1

Comparison of TSH suppression

Study		n		Thyroxine dose/day		Cases of TSH suppression (%)		Definition of TSH suppression
Study		n		Thyroxine dose/day		3 months	6 months	Definition of TSH suppression	12 months
London¹	32	100 μg/m²	19	37	72	< 6 mU/l
SW England⁸	42	Variable	48	62	67	< 10 mU/l
Leicester	25^*	37.5 μg	52	80	88	< 10 mU/l
Norway⁵	42	50 μg	86	–	–	< 10 mU/l

1-150 Four cases excluded: one because of definite non-compliance and three because of late treatment in mildly affected cases.