Summary of changes (mean (SEM)) in Pao 2/Fio 2, oxygenation index, ventilation index, and mean systemic arterial pressure with inhaled nitric oxide for all patients
| Baseline | 1 ppm | 10 ppm | 20 ppm | On discontinuation of iNO | |
|---|---|---|---|---|---|
| Pao 2/Fio 2(kPa) | 11.9 (1.7) | 20 (3.9)* | 24 (4.5)* | 21.6 (3.9)* | 14.3 (2.5) |
| OI | 28.3 (5) | 18 (3)* | 15 (3)* | 16 (3)* | 24 (4) |
| VI | 43.8 (6.3) | 39.1 (5.0) | 39.1 (5.2) | 38.9 (5.3) | 42.1 (7.5) |
| mSAP | 60 (2) | 63 (4) | 65 (4) | 67 (3) | 61 (4) |
OI, oxygenation index; VI, ventilation index; mSAP, mean systemic arterial pressure. *p < 0.05.