Relative risk of SIDS for the dichotomised daily caffeine consumption variable in the first and third trimesters, and all pregnancy
| Caffeine consumption (mg/day) | No (%) SIDS infants | No (%) control infants | OR (95% CI) unadjusted† | OR (95% CI) adjusted‡ |
|---|---|---|---|---|
| First trimester | ||||
| Non-heavy (0–399) | 263 (69.8) | 1293 (81.8) | 1.00 | 1.00 |
| Heavy (⩾400) | 114 (30.2) | 288 (18.2) | 1.95 (1.51 to 2.52)*** | 1.30 (0.92 to 1.82) |
| Third trimester | ||||
| Non-heavy (0–399) | 259 (68.7) | 1303 (82.4) | 1.00 | 1.00 |
| Heavy (⩾400) | 118 (31.3) | 278 (17.6) | 2.14 (1.66 to 2.76)*** | 1.46 (1.05 to 2.05)* |
| All pregnancy (both first and third trimesters) | ||||
| Non-heavy (0–399) | 271 (71.9) | 1359 (86.0) | 1.00 | 1.00 |
| Heavy (⩾400) | 106 (28.1) | 222 (14.0) | 2.42 (1.85 to 3.15)*** | 1.65 (1.15 to 2.36)** |
2-151 Adjusted for infants’ age only.
2-152 Adjusted for confounding factors listed in the . Wald statistic p values: *p<0.05, **p<0.01, ***p<0.001.