Table 1

Clinical and immunological data of the 13 cases who had repeat serology approximately four years after aciclovir prophylaxis

Antibody titres to VZV
Case No Age1-151 (years) Sex Dose of aciclovir (mg/kg/day) Duration of observation period (months) Re-exposure of varicella during the observation period At the time of convalescent phase of aciclovir prophylaxis Four years after aciclovir prophylaxis1-152
11M8050No164
29M8046No88
31F2045No88
40.4M2038No<44
53M2035No2564
60.6F533No88
74F1845No1284
81-150 0.5F4045Yes<48
91M2037Yes648
101-150 1M4038Yes<416
114M3048Yes1616
122F1845Yes816
131-150 0.5F4047Yes864
  • 1-150 These three cases showed an antibody rise during the observation period.

  • 1-151 Represents age at the time of aciclovir prophylaxis.

  • 1-152 Antibody titres in cases 8 to 13 were significantly higher than those in cases 1 to 7 (p<0.01).