Mean (SD) sputum concentrations of tobramycin (mg/l) on day 14
| Time2-150 | Group A | Group B |
|---|---|---|
| H1 | 1.4 (0.9) (n = 6) | 2.8 (1.4) (n = 4) |
| H2 | 1.9 (1.6) (n = 8) | 3.2 (0.9) (n = 7) |
| H3† | 1.7 (1.6) (n = 7) | 4.9 (2.8) (n = 9) |
| H4† | 1.3 (0.8) (n = 7) | 3.5 (1.9) (n = 9) |
| H8 | 1.0 (0.7) (n = 6) | 1.9 (0.7 (n = 5) |
Group A, thrice daily infusions of tobramycin; group B, once daily infusions of tobramycin. n, number of measurements at each time.
↵2-150 Hours after infusion; †p < 0.02 group A v group B.