Growth and treatment data
| Patient No | Age start (years) | Stage of renal failure | Pretrial Ht SD | 2 Year Ht SD | Height Δ score | Duration GH (months) | Comments | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Start | 2 Years | ||||||||||||||||||
| 1 | 16.2 | Trans | Trans | −5.8 | −4.0 | 1.8 | 24 | ||||||||||||
| 2 | 4.5 | Pre-D | Pre-D | −2.7 | −1.0 | 1.7 | 24 | ||||||||||||
| 3 | 15.7 | Dial | Trans | −2.3 | −0.6 | 1.7 | 11 | Withdrawn at 11 months: transplant | |||||||||||
| G | 4 | 9.0 | Dial | Dial | −3.1 | −1.5 | 1.6 | 24 | Side effects: priapism | ||||||||||
| O | 5 | 6.8 | Pre-D | Trans | −2.9 | −1.3 | 1.6 | 8 | Withdrawn at 8 months: decreased GFR | ||||||||||
| O | 6 | 5.0 | Pre-D | Dial | −2.5 | −1.2 | 1.3 | 24 | |||||||||||
| D2-150 | 7 | 16.4 | Trans | Trans | −4.5 | −3.2 | 1.3 | 12 | Withdrawn at 12 months: decreased GFR | ||||||||||
| 8 | 9.2 | Trans | Trans | −3.0 | −1.8 | 1.2 | 14 | Withdrawn at 14 months: transplant | |||||||||||
| 9 | 9.8 | Trans | Trans | −2.7 | −1.5 | 1.2 | 24 | ||||||||||||
| 10 | 4.6 | Pre-D | Pre-D | −3.5 | −2.4 | 1.1 | 24 | ||||||||||||
| 11 | 4.2 | Dial | Trans | −2.8 | −1.7 | 1.1 | 4 | Withdrawn at 4 months: transplant | |||||||||||
| 12 | 3.7 | Dial | Dial | −3.6 | −2.6 | 1.0 | 24 | Side effects: avascular necrosis | |||||||||||
| M | 13 | 15.5 | Dial | Dial | −4.1 | −3.4 | 0.7 | 12 | Withdrawn 1 year no response | ||||||||||
| O | 14 | 6.9 | Pre-D | Pre-D | −2.3 | −1.7 | 0.6 | 24 | |||||||||||
| D | 15 | 9.7 | Dial | Dial | −3.0 | −2.5 | 0.5 | 24 | |||||||||||
| E | 16 | 2.0 | Pre-D | Pre-D | −2.9 | −2.6 | 0.3 | 0 | Refused GH trial | ||||||||||
| R | 17 | 5.9 | Pre-D | Pre-D | −3.0 | −2.7 | 0.3 | 13 | Withdrawn at 13 months: small decrease GFR | ||||||||||
| A | 18 | 18.7 | Trans | Trans | −2.3 | −2.0 | 0.3 | 4 | Side effects:chest pain (patient withdrew himself) | ||||||||||
| T | 19 | 14.4 | Trans | Trans | −1.8 | −1.5 | 0.3 | 24 | |||||||||||
| E2-150 | 20 | 4.1 | Dial | Trans | −3.7 | −3.5 | 0.2 | 7 | Withdrawn at 7 months: transplant | ||||||||||
| 21 | 15.2 | Trans | Trans | −4.3 | −4.3 | .0 | 12 | Side effects: minor weight gain; withdrawn 1yr no response | |||||||||||
| 22 | 13.2 | Trans | Dial | −2.8 | −2.9 | −0.1 | 24 | Side effects: small decrease GFR | |||||||||||
| 23 | 8.7 | Pre-D | Pre-D | −3.5 | −3.7 | −0.2 | 7 | Withdrawn at 7 months: transplant (failed) | |||||||||||
| P | 24 | 4.7 | Dial | Dial | −3.0 | −3.3 | −0.3 | 15 | Withdrawn at 15 months: fits | ||||||||||
| O | 25 | 11.8 | Dial | Dial | −1.9 | −2.3 | −0.4 | 3 | Withdrawn at 3 months: headaches, increase ICP | ||||||||||
| O | 26 | 12.7 | Dial | Dial | −3.3 | −4.0 | −0.7 | 22 | Withdrawn at 22 months: no response | ||||||||||
| R2-150 | 27 | 12.7 | Dial | Dial | −1.7 | −2.6 | −0.9 | 12 | Withdrawn at 12 months: no response | ||||||||||
| 28 | 13.2 | Dial | Dial | −5.3 | −6.3 | −1.0 | 12 | Withdrawn at 12 months: poor response | |||||||||||
| 29 | 12.4 | Trans | Trans | −2.1 | −3.7 | −1.6 | 0 | Refused GH trial | |||||||||||
| 30 | 6.0 | Dial | Trans | −3.5 | 16 | Withdrawn at 16 months: transplant | |||||||||||||
↵2-150 Growth during the study. See methods for detail. Dial = dialysis; GFR = glomerular filtration rate; GH = growth hormone; Ht SD = height standard deviation; ICP = intracranial pressure; Pre-D = predialysis; Trans = transplant.