Table 1

Diagnostic criteria for Marfan’s syndrome according to the Berlin nosology 1986

Cardiovascular Dilation of ascending aorta*
Aortic dissection*
Mitral regurgitation
Mitral valve prolapse
Abdominal aortic aneurysm
Ophthalmic Ectopia lentis*
Severe myopia
Retinal detachment, flat cornea, and  elongated globe
Neurological Dural ectasia*
Respiratory/integument Pneumothorax
Striae
Herniae
Skeletal Chest wall deformity
Vertebral column deformity
Arachnodactyly
Narrow, high arched palate
Tall stature
Limb disproportion
Abnormal joint mobility
Protusio acetabuli
  • In the absence of a definitely affected first degree relative, there should be skeletal involvement plus involvement of two other systems, one with a major manifestation. *Two system involvement with one major manifestation is required when a first degree relative is affected.