Table 1

Protocol for endoscopic sedation

Oral premedication
 UGIEMidazolam (<2 years, 2 mg; >2 years, 4 mg)
 ColonoscopyChloral hydrate (50 mg/kg, max 2000 mg) and  chlorpromazine (1 mg/kg, max 25 mg)
IV sedation (for both UGIE and colonoscopy)
Pethidine Initial dose 1 mg/kg
 0.5–1 mg/kg boluses; maximum permitted dose 2.5  mg/kg
 Midazolam0.05–0.1 mg/kg boluses; maximum permitted dose 0.75  mg/kg (but never more than 15 mg total dose)
  • UGIE = upper gastrointestinal endoscopy.