Table 2

Baseline sputum imflammatory markers (median with interquartile range) and mean coefficient of variation (%) with median (95% CI) change from baseline after treatment with fluticasone propionate and placebo. Also included are estimated median treatment differences (fluticasone propionate minus placebo) with 95% CI. Values of p > 0.05 are considered non-significant (NS)

Interleukin-8 (pg/ml)TNF-α(pg/ml)Free neutrophil elastase (u/ml)
Baseline376 (306 to 437)375 (198 to 583)62 (40 to 80)
Coefficient of variation (%)54 30 26 
Fluticasone propionate8 (−161 to 217)14 (−90 to 103)−1 (−8 to 14)
Placebo−67 (−1152 to 37)25 (−122 to 117)1 (−15 to 7)
Estimated median treatment difference142 (8 to 2866)27 (−104 to 167)5 (−9 to 31)
p Value0.03 NS NS