Production of new boosted protective vaccine responses to the three influenza antigens, H1N1, H2N3, and B, in children vertically infected with HIV. Stratified according to clinical and immunological status: Clinical groups: N/A, no/minimal symptoms; B, moderate symptoms; C, severe symptoms or AIDS. Immunological groups: 1, no immunosuppression; 2, moderate immunosuppression; 3, severe immunosuppression
| Clinical status | Immunological status | |||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| N/A (n=7) | B (n=13) | C (n=5) | 1 (n=8) | 2 (n=9) | 3 (n=8) | |||||||||||||
| Protective new antibody response to 1,2, or 3 influenza antigens | 1 | 2 | 3 | 1 | 2 | 3 | 1 | 2 | 3 | 1 | 2 | 3 | 1 | 2 | 3 | 1 | 2 | 3 |
| No of responders | 5 | — | 1 | 1 | 2 | — | 1 | — | — | 3 | — | — | 3 | 1 | 1 | 1 | 1 | — |
| Proportion responding to vaccine | 0.86 | 0.23 | 0.2 | 0.38 | 0.56 | 0.25 | ||||||||||||