Table 3

The 1982 criteria for the classification of SLE. A diagnosis of SLE can be made with 98% specificity and 97% sensitivity if four of the criteria listed below are present at any time5

Diagnostic criteria of the American Rheumatism AssociationPatient 1Patient 2
Malar rashYes
Discoid rash
Oral ulcersYes
Arthritis (non-erosive arthritis involving two or more peripheral joints, characterised by tenderness, swelling, or effusion)Yes
Serositis (pleuritis or pericarditis)Yes
Renal disorder (proteinuria > 5.0 g/dl or 3+ protein, or cellular casts)Yes
Neurological disorder
Haematological disorder (haemolytic anaemia, leukopenia, lymphopenia, or thrombocytopenia)YesYes
Immunological disorder (positive LE cell preparation or anti-dsDNA or anti-Sm antibodies or false positive VDRL)YesYes
Antinuclear antibodiesYesYes