Table 2

Immunological results—patients 1 and 2

AgedsDNAANAOthersComplement
Patient 17 yr 8 mNot doneNot doneIgG 22.2 g/l (7.68-11.28)CH50:15 U/ml (25-45)
IgA 3.58 g/l (0.77-1.67)C3:0.38 g/l (0.8-1.9)
IgM 0.65 g/l (0.57-2.66)C4:0.09 g/l (0.2-0.4)
8 yr 9 mPos > 1000 IU/mlIgG Pos 1/1000 H(620 IU/ml)pANCA neg
(N < 8 U/ml)IgM Pos 1/40 HcANCA neg
SCAT neg (< 1/16)
Ph latex neg (< 1/40)
Patient 22 yr 6 mPos 9 IU/mlNegativeCH50:45 U/ml (25-45)
(N < 8)C3:1.62 g/l (0.8-1.40)
C4:0.21 g/l (0.15-0.40)
3 yr 2 m5 IU/ml negNegative
3 yr 7 m25 IU/ml posIgG ANA Ab Pos (1/40) H(12 IU/ml)IgG 27.40 g/l (7.09-10.75)
IgM ANA Ab Neg (1/10)IgA 3.06 g/l (0.34-1.08)
IgM 5.68 g/l (0.42-0.80)
3 yr 8 mAnticardiolipin: 14 GPLU (normal 0-10)C3:1.48
pANCA—pos 1/64C4:0.19
cANCA—neg
3 yr 9 m18 IU/ml posIgG ANA pos 1/100(31 IU/ml)Anticardiolipin 10 GPLUCH50:38
IgM ANA negC3:1.42
C4:0.16
4 yr5 IU/ml negIgG ANA pos 1/100(31 IU/ml)Anticardiolipin 6 GPLUC3:1.25
IgM ANA 1/10C4:0.19
4 yr 2 m4 IU/ml negIgG ANA pos 1/80 H(25 IU/ml)C3:1.45
IgM ANA pos 1/20 HC4:0.24
4 yr 5 m3 IU/ml negIgG ANA 1/20 pos H(6 IU/ml)IgG 18.60 g/l (6.73-11.11)C3:1.53
IgM ANA 1/10 HIgA 2.98 g/l (0.65-1.18)C4:0.26
IgM 2.78 g/l (0.36-0.70)
4 yr 7 m6 IU/ml negIgG ANA pos 1/80 H(25 IU/ml)pANCA pos (1/512)C3:1.46
IgM ANA negcANCA negC4:0.29
Antibodies to serine proteinase 3 (PR3): neg
Antibodies to myeloperoxidase (MPO): neg
  • N = normal; H = homogeneous; dsDNA = double stranded DNA; ANA = antinuclear antibodies; pANCA = perinuclear antineutrophil cytoplasmic antibody; cANCA = classical anti-neutrophil cytoplasmic antibody; GPLU = IgG phospholipid units.