@article {Plumb1043, author = {Lucy Plumb and Winnie Magadi and Anna Casula and Ben C Reynolds and Mairead Convery and Shuman Haq and Shivaram Hegde and Andrew Lunn and Michal Malina and Henry Morgan and Mordi Muorah and Kay Tyerman and Manish D Sinha and Dean Wallace and Carol Inward and Stephen Marks and Dorothea Nitsch and James Medcalf}, title = {Advanced chronic kidney disease among UK children}, volume = {107}, number = {11}, pages = {1043--1045}, year = {2022}, doi = {10.1136/archdischild-2021-323686}, publisher = {BMJ Publishing Group Ltd}, abstract = {The UK Renal Registry currently collects information on UK children with kidney failure requiring long-term kidney replacement therapy (KRT), which supports disease surveillance and auditing of care and outcomes; however, data are limited on children with chronic kidney disease (CKD) not on KRT.Methods In March 2020, all UK Paediatric Nephrology centres submitted data on children aged \<16 years with severely reduced kidney function as of December 2019, defined as an estimated glomerular filtration rate \<30 mL/min/1.73 m2.Results In total, 1031 children had severe CKD, the majority of whom (80.7\%) were on KRT. The overall prevalence was 81.2 (95\% CI 76.3 to 86.3) per million of the age-related population.Conclusions The prevalence of severe CKD among UK children is largely due to a high proportion of children on long-term KRT. Expanding data capture to include children with CKD before reaching failure will provide greater understanding of the CKD burden in childhood.}, issn = {0003-9888}, URL = {https://adc.bmj.com/content/107/11/1043}, eprint = {https://adc.bmj.com/content/107/11/1043.full.pdf}, journal = {Archives of Disease in Childhood} }