RT Journal Article
SR Electronic
T1 Advanced chronic kidney disease among UK children
JF Archives of Disease in Childhood
JO Arch Dis Child
FD BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health
SP archdischild-2021-323686
DO 10.1136/archdischild-2021-323686
A1 Plumb, Lucy
A1 Magadi, Winnie
A1 Casula, Anna
A1 Reynolds, Ben C
A1 Convery, Mairead
A1 Haq, Shuman
A1 Hegde, Shivaram
A1 Lunn, Andrew
A1 Malina, Michal
A1 Morgan, Henry
A1 Muorah, Mordi
A1 Tyerman, Kay
A1 Sinha, Manish D
A1 Wallace, Dean
A1 Inward, Carol
A1 Marks, Stephen
A1 Nitsch, Dorothea
A1 Medcalf, James
YR 2022
UL http://adc.bmj.com/content/early/2022/06/21/archdischild-2021-323686.abstract
AB The UK Renal Registry currently collects information on UK children with kidney failure requiring long-term kidney replacement therapy (KRT), which supports disease surveillance and auditing of care and outcomes; however, data are limited on children with chronic kidney disease (CKD) not on KRT.Methods In March 2020, all UK Paediatric Nephrology centres submitted data on children aged <16 years with severely reduced kidney function as of December 2019, defined as an estimated glomerular filtration rate <30 mL/min/1.73 m2.Results In total, 1031 children had severe CKD, the majority of whom (80.7%) were on KRT. The overall prevalence was 81.2 (95% CI 76.3 to 86.3) per million of the age-related population.Conclusions The prevalence of severe CKD among UK children is largely due to a high proportion of children on long-term KRT. Expanding data capture to include children with CKD before reaching failure will provide greater understanding of the CKD burden in childhood.