RT Journal Article SR Electronic T1 Sharing a household with children and risk of COVID-19: a study of over 300 000 adults living in healthcare worker households in Scotland JF Archives of Disease in Childhood JO Arch Dis Child FD BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health SP 1212 OP 1217 DO 10.1136/archdischild-2021-321604 VO 106 IS 12 A1 Rachael Wood A1 Emma Thomson A1 Robert Galbraith A1 Ciara Gribben A1 David Caldwell A1 Jennifer Bishop A1 Martin Reid A1 Anoop S V Shah A1 Kate Templeton A1 David Goldberg A1 Chris Robertson A1 Sharon J Hutchinson A1 Helen M Colhoun A1 Paul M McKeigue A1 David A McAllister YR 2021 UL http://adc.bmj.com/content/106/12/1212.abstract AB Objective Children are relatively protected from COVID-19, due to a range of potential mechanisms. We investigated if contact with children also affords adults a degree of protection from COVID-19.Design Cohort study based on linked administrative data.Setting Scotland.Study population All National Health Service Scotland healthcare workers and their household contacts as of March 2020.Main exposure Number of young children (0–11 years) living in the participant’s household.Main outcomes COVID-19 requiring hospitalisation, and any COVID-19 (any positive test for SARS-CoV-2) in adults aged ≥18 years between 1 March and 12 October 2020.Results 241 266, 41 198, 23 783 and 3850 adults shared a household with 0, 1, 2 and 3 or more young children, respectively. Over the study period, the risk of COVID-19 requiring hospitalisation was reduced progressively with increasing numbers of household children—fully adjusted HR (aHR) 0.93 per child (95% CI 0.79 to 1.10). The risk of any COVID-19 was similarly reduced, with the association being statistically significant (aHR per child 0.93; 95% CI 0.88 to 0.98). After schools reopened to all children in August 2020, no association was seen between exposure to young children and risk of any COVID-19 (aHR per child 1.03; 95% CI 0.92 to 1.14).Conclusion Between March and October 2020, living with young children was associated with an attenuated risk of any COVID-19 and COVID-19 requiring hospitalisation among adults living in healthcare worker households. There was no evidence that living with young children increased adults’ risk of COVID-19, including during the period after schools reopened.Data may be obtained from a third party and are not publicly available. Data may be accessed via a secure platform following successful application to the Public Benefit and Privacy Panel via application to the electronic Data Research Information Services of Public Health Scotland.