TY - JOUR T1 - Sharing a household with children and risk of COVID-19: a study of over 300 000 adults living in healthcare worker households in Scotland JF - Archives of Disease in Childhood JO - Arch Dis Child SP - 1212 LP - 1217 DO - 10.1136/archdischild-2021-321604 VL - 106 IS - 12 AU - Rachael Wood AU - Emma Thomson AU - Robert Galbraith AU - Ciara Gribben AU - David Caldwell AU - Jennifer Bishop AU - Martin Reid AU - Anoop S V Shah AU - Kate Templeton AU - David Goldberg AU - Chris Robertson AU - Sharon J Hutchinson AU - Helen M Colhoun AU - Paul M McKeigue AU - David A McAllister Y1 - 2021/12/01 UR - http://adc.bmj.com/content/106/12/1212.abstract N2 - Objective Children are relatively protected from COVID-19, due to a range of potential mechanisms. We investigated if contact with children also affords adults a degree of protection from COVID-19.Design Cohort study based on linked administrative data.Setting Scotland.Study population All National Health Service Scotland healthcare workers and their household contacts as of March 2020.Main exposure Number of young children (0–11 years) living in the participant’s household.Main outcomes COVID-19 requiring hospitalisation, and any COVID-19 (any positive test for SARS-CoV-2) in adults aged ≥18 years between 1 March and 12 October 2020.Results 241 266, 41 198, 23 783 and 3850 adults shared a household with 0, 1, 2 and 3 or more young children, respectively. Over the study period, the risk of COVID-19 requiring hospitalisation was reduced progressively with increasing numbers of household children—fully adjusted HR (aHR) 0.93 per child (95% CI 0.79 to 1.10). The risk of any COVID-19 was similarly reduced, with the association being statistically significant (aHR per child 0.93; 95% CI 0.88 to 0.98). After schools reopened to all children in August 2020, no association was seen between exposure to young children and risk of any COVID-19 (aHR per child 1.03; 95% CI 0.92 to 1.14).Conclusion Between March and October 2020, living with young children was associated with an attenuated risk of any COVID-19 and COVID-19 requiring hospitalisation among adults living in healthcare worker households. There was no evidence that living with young children increased adults’ risk of COVID-19, including during the period after schools reopened.Data may be obtained from a third party and are not publicly available. Data may be accessed via a secure platform following successful application to the Public Benefit and Privacy Panel via application to the electronic Data Research Information Services of Public Health Scotland. ER -