RT Journal Article
SR Electronic
T1 Prevalence of thrombotic complications in children with SARS-CoV-2
JF Archives of Disease in Childhood
JO Arch Dis Child
FD BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health
SP archdischild-2020-321351
DO 10.1136/archdischild-2020-321351
A1 David Aguilera-Alonso
A1 Sara Murias
A1 Amelia Martínez-de-Azagra Garde
A1 Antoni Soriano-Arandes,
A1 Marta Pareja
A1 Enrique Otheo
A1 Cinta Moraleda
A1 Alfredo Tagarro
A1 Cristina Calvo
A1 ,
YR 2021
UL http://adc.bmj.com/content/early/2021/05/24/archdischild-2020-321351.abstract
AB Knowledge of thrombosis in children with SARS-CoV-2 is scarce. In this multicentre national cohort of children with SARS-CoV-2 involving 49 hospitals, 4 patients out of 537 infected children developed a thrombotic complication (prevalence of 0.7% (95% CI: 0.2% to 1.9%) out of the global cohort and 1.1% (95% CI: 0.3% to 2.8%) out of the hospitalised patients). We describe their characteristics and review other published paediatric cases. Three out of the four patients were adolescent girls, and only two cases had significant thrombotic risk factors. In this paediatric cohort, D-dimer value was not specific enough to predict thrombotic complications. Adolescence and previous thrombotic risk factors may be considered when initiating anticoagulant prophylaxis on children with SARS-CoV-2 disease (COVID-19).All data relevant to the study are included in the article or uploaded as supplemental information.